Pelling
Lab.net
Laboratory for Biophysical Manipulation
University of Ottawa
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Journal Articles

2012

27. Al-Rekabi & Pelling, A.E. Under Review (2012). 

26. Modulevsky, D.J. & Pelling, A.E. Under Review (2012).

25. Guolla, L., Bertrand, M., Haase, K. & Pelling, A.E. "Force Transduction and Strain Dynamics in Actin Stress Fibres in Response to Nanonewton Forces." J Cell Science In Press (2012).

24. Wang, J & Pelling, A.E. "An Approach to Visualize the Deformation of the Intermediate Filament Cytoskeleton in Response to Locally Applied Forces." ISRN Cell Biology 2012, Article ID 513546, 9 pages (2012) [PDF].

2011

23. Hemsley, A.L., Hernandez, D., Pelling, A.E. & Veraitch, F.S. "Precisely delivered nano-mechanical forces induce blebbing in undifferentiated mouse embryonic stem cells." Cell Health and Cytoskeleton 3, 23 (2011) [PDF].

2010

22. Wang, J. & Pelling, A.E. "Cell Sheet Integrity and Nanomechanical Breakdown During Programmed Cell Death." Med Biol Eng Comput 48, 1015 (2010) [PDF].

2009

21. Silberberg, Y.S., Yakubov, G.E., Horton, M.A. & Pelling, A.E. "Cell Nanomechanics and Focal Adhesions are Regulated by Retinol and Conjugated Linoleic Acid in a Dose Dependent Manner." Nanotechnology 20, 285103 (2009) [PDF].

20. Pelling, A.E., Veraitch, F.S., Chu, C.P.K., Mason, C. & Horton, M.A. "Mechanical Dynamics of Single Cells During Early Apoptosis." Cell Motil Cytoskeleton 66, 409 (2009) [Cover Article - PDF].

19. Hogan, C., Dupre-Crochet, S., Norman, M., Kajita, M., Zimmermann, C., Pelling, A.E., Piddini, E., Baena-Lopez, A., Vincent, J., Itoh, Y., Hosoya, H., Pichaud, F. & Fujita, Y. "Characterization of the Interface Between Normal and Transformed Epithelial Cells." Nat Cell Biol 11, 460 (2009) [PDF].

18. Pelling, A.E., Wilkinson, P.R., Stringer, R.P. & Gimzewski, J.K. "Dynamic Mechanical Oscillations During Metamorphosis of the Monarch Butterfly." J Roy Soc Interface 6, 29 (2009) [Cover Article - PDF].

2008

17. Silberberg, Y.R., Pelling, A.E., Yakubov, G.E., Crum, W.R., Hawkes, D.J. & Horton, M.A. "Tracking Displacements of intracellular Organelles in Response to Nanomechanical Forces." Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on. 1335-1338 (2008) [PDF].

16. Kunda, P., Pelling, A.E., Liu, T. & Baum, B. "Moesin Controls Cortical Rigidity, Cell Rounding and Spindle Assembly During Mitosis." Curr Biol 18, 91 (2008) [PDF] [Developmental Cell Previews] [Nature Cell Biology News & Views] [Current Biology Dispatches].

15. Silberberg, Y.R., Pelling, A.E., Yakubov, G.E., Crum, W.R., Hawkes, D.J. & Horton, M.A. "Mitochondrial Displacements in Response to Nanomechanical Forces." J Mol Recognit 21, 30 (2008) [PDF].

14. Pelling, A.E. & Horton, M.A. "An Historical Perspective on Cell Mechanics." Pflügers Archiv - Eur J Physiol 456, 3 (2008) [PDF].

2007

13. Pelling, A.E., Veraitch, F.S., Chu, C.P.K., Nicholls, B.M., Hemsley, A.L., Mason, C. & Horton, M.A. "Mapping Correlated Membrane Pulsations and Fluctuations in Human Cells." J Mol Recognit 20, 467 (2007) [PDF].

12. Pelling, A. E., Dawson, D. W., Carreon, D. M., Christiansen, J. J., Shen, R. R., Teitell, M. A. & Gimzewski, J. K. "Distinct Contributions of Microtubule Subtypes to Cell Membrane Shape and Stability." Nanomedicine 3, 43 (2007) [PDF].

2006

11. Haupt, B.J., Pelling, A.E. & Horton, M.A. "Integrated Confocal and Scanning Probe Microscopy for Biomedical Research." ScientificWorldJournal 6, 1609 (2006) [PDF].

10. Pelling, A.E., Li, Y., Cross, S.E., Castaneda, S., Shi, W. & Gimzewski, J.K. "Self-Organized and Highly Ordered Domains within Swarms of Myxococcus xanthus." Cell Motil Cytoskeleton 63, 141 (2006) [Cover Article - PDF]

9. Cross, S.E., Kreth, J., Zhu, L., Qi, F., Pelling, A.E., Shi, W. & Gimzewski, J.K. "Atomic Force Microscopy Study of the Structure-Function Relationships of the Biofilm-Forming Bacterium Streptococcus mutans." Nanotechnology 17, S1 (2006) [PDF].

2005

8. Han, T.H., Pelling, A.E., Jeon, T., Gimzewski, J.K. & Liao, J. "Erythrocyte Nitric Oxide Transport Reduced by a Submembrane Cytoskeletal Barrier." Biochim Biophys Acta 1726, 336 (2005) [PDF] and [Original Article].

7. Pelling, A.E., Sehati, S., Gralla, E.B. & Gimzewski, J.K. "Time Dependence of the Frequency and Amplitude of the Local Nanomechanical Motion of Yeast." Nanomedicine 1, 178 (2005) [PDF].

6. Pelling, A.E., Li, Y., Shi, W. & Gimzewski, J.K. "Nanoscale Visualization and Characterization of Myxococcus xanthus Cells with Atomic Force Microscopy." Proc Natl Acad Sci USA 102, 6484 (2005) [PDF].

5. Li, Y., Lux, R., Pelling, A.E., Gimzewski, J.K. & Shi, W. "Analysis of Type IV Pilus and Its Associated Motility in Myxococcus xanthus Using an Antibody Reactive with Native Pilin and Pili." Microbiology 151, 353 (2005) [PDF].

2004

4. Rong, W., Pelling, A.E., Ryan, A., Gimzewski, J.K. & Friedlander, S.K. "Complementary TEM and AFM Force Spectroscopy to Characterize the Nanomechanical Properties of Nanoparticle Chain Aggregates." Nano Lett 4, 2287 (2004) [PDF] [Nature Materials Nanozone News].

3. Sattin, B.D., Pelling, A.E. & Goh. M.C. "DNA Base Pair Resolution by Single Molecule Force Spectroscopy." Nuc Acids Res 32, 4876 (2004) [PDF].

2. Pelling, A.E., Sehati, S., Gralla, E.B., Valentine, J.S. & Gimzewski, J.K. "Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae." Science 304, 1147 (2004) [PDF] [This Week In Science] [Nature News] [Analytical Chemistry News] [Smithsonian Magazine] [Der Spiegel].

2000

1. Pezacki, J.P., Pelling, A. & Kluger, R. "S-Nitrosylation of Cross-Linked Hemoglobins at b-Cysteine-93: Stabilized Hemoglobins as Nitric Oxide Sources." J Am Chem Soc 122, 10734 (2000) [PDF].


Book Chapters

7. Al-Rekabi, Z., Tremblay, D. Haase, K., Leask, R.L. & Pelling, A.E. "Computational and Experimental Approaches to Cellular and Subcellular Tracking at the Nanoscale." Musa, S.M. ed. Computational Nanotechnology: Modeling and Applications with MATLAB. New York: CRC Press, pp.333-361 (2011).

6. Silberberg, Y.R., Guolla, L. & Pelling, A.E. "Investigating Mammalian Cell Nanomechanics with Simultaneous Optical and Atomic Force Microscopy." Dufrene, Y.F. ed. Life at the Nanoscale: Atomic Force Microscopy of Live Cells. Singapore: Pan Stanford Publishing, pp.375-401 (2011).

5. Al-Rekabi, Z., Harden, J.L. & Pelling, A.E. "Cellular Nanomechanics in Nanomedicine." In Bartul, Z. & Trenor, J. eds. Advances in Nanotechnology Volume 2. New York: Nova Science Publishers, pp.275-296 (2010).

4. Niemetz, A. & Pelling, A.E. "Dark Side of the Cell III." In Kwong, J., To, D. and Ng, N. eds. Transient Creatures. Hong Kong: Microwave, pp.80-83 (2008) [PDF].

3. Pelling, A.E., Nicholls, B.M., Silberberg, Y.S. & Horton, M.A. "Approaches for Investigating Mechanobiologial Dynamics in Living Cells with Combined Fluorescence and Atomic Force Microscopies." In Méndez-Vilas, A. and Díaz, J. eds. Modern Research and Educational Topics on Microscopy. Badajoz: Formatex, pp.3-10 (2007) [PDF].

2. Pelling, A.E. & Niemetz, A. "Cellular Sounds." In Mol, J.V. ed. The Nano Research. Ad!dict Inspiration Book #27. Brussles: Ad!dict Lab, pp.24-27 (2007) [online].

1. Niemetz, A. & Pelling, A.E. "Singende Zellen, Kunst, Wissenschaft und das Bauschen dazwischen." In: B. Könches, P. Weibel, eds. unSICHTBARes Kunst und Wissenschaft. Bern: Benteli Verlag, pp.322-337 (2005) [online].


US Patents and Invention Disclosures

3. Pelling, A.E. & Gimzewski, J.K. "Directed Mechanotaxis of Single Cells with Local Probes." (UC Case No. 2005-599).

2. Gimzewski, J.K., Pelling, A.E. & Ventura, C. (WO/2008/105919) Nanomechanical Characterization of Cellular Activity. Application # PCT/US2007/076283, Filed August 20, 2007.

1. Gimzewski, J.K. & Pelling, A.E. (WO/2005/003290) Methods and devices for determining a cell characteristic, and applications employing the same. Application # PCT/US2003/028066, Filed September 8, 2003.


Non-refereed Publications

3. Pelling, A. E., Sehati, S., Gralla, E. B., Valentine, J. S., and Gimzewski, J.K. "Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae." Phantoms Newsletter 17, 33 (2004) [PDF].

2. Pelling, A. E. and Hayes R. L. "Grabbing the Cat by the Tail." CNSI Spheres Magazine 2, 10 (2004) [PDF].

1. Hayes R. L. and Pelling, A. E. "De Novo Predictions of Nanoscale and Nanoelectronic Systems." CNSI Spheres Magazine 1, 10 (2003) [PDF].